METHOD OF USING M1-SELECTIVE ANTIMUSCARINIC PYRIDOBENZODIAZEPIONES IN AXIAL MYOPIA THERAPY

摘要

163FPG/ - i - 18651 TITLE OF THE INVENTION METHOD OF USING M1-SELECTIVE ANTIMUSCARINIC PYRIDOBENZODIAZEPINONES IN AXIAL MYOPIA THERAPY Pyridobenzodiazepinones of the formula: wherein R is piperidine substituted by C1-C5 alkyl, are ocularyl administered to animals to prevent abnormal increases in eye axial length and thereby 163FPG/ - ii - 18651 arrest the progression of axial myopia. The compounds are pharmacologically characterized in that they selectively antagonize the binding of acetylcholine to M1-type muscarine receptors.