首页> 外国专利> Imidazoylalkyl Substituted with a Six Membered Nitrogen Containing Heterocyclic Ring

Imidazoylalkyl Substituted with a Six Membered Nitrogen Containing Heterocyclic Ring

机译:含杂环杂环的六元氮取代的咪唑烷基

摘要

Disclosed is a compound of formula (1.0) or a pharmaceutically acceptable salt or solvate thereof. Also disclosed are pharmaceutical compositions comprising a pharmaceutically acceptable carrier and an effective amount of a compound of formula (1.0). Further disclosed is a method of treating allergy (for example asthma), inflammation, hypertension, raised intraocular pressure (such as glaucoma), i.e., a method of lowering intraocular pressure, sleeping disorders, states of hyper and hypo motility and acidic secretion of the gastrointestinal tract, hypo and hyperactivity of the central nervous system (for example, agitation and depression) and other CNS disorders (such as Alzheimers, Schizophrenia, and migraine) comprising administering an effective amount of a compound of formula (1.0) to a patient in need of such treatment.
机译:公开了式(1.0)的化合物或其药学上可接受的盐或溶剂化物。还公开了包含药学上可接受的载体和有效量的式(1.0)化合物的药物组合物。进一步公开了一种治疗变态反应(例如哮喘),炎症,高血压,眼内压升高(例如青光眼)的方法,即降低眼内压,睡眠障碍,高动力和低动力状态以及酸性分泌的方法。胃肠道,中枢神经系统功能低下和亢进(例如躁动和抑郁)和其他中枢神经系统疾病(例如阿尔茨海默氏症,精神分裂症和偏头痛),包括向患者服用有效量的式(1.0)化合物需要这种治疗。

著录项

  • 公开/公告号CA2126086A1

    专利类型

  • 公开/公告日1993-06-24

    原文格式PDF

  • 申请/专利权人 SCHERING CORP;

    申请/专利号CA19922126086

  • 发明设计人 SHIH NENG-YANG;GREEN MICHAEL J;

    申请日1992-12-16

  • 分类号C07D401/06;A61K31/445;

  • 国家 CA

  • 入库时间 2022-08-22 05:08:14

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