METHODS AND COMPOSITIONS FOR NEUTRALIZING INTRACELLULAR NUCLEIC ACID-BINDING PROTEIN BIOLOGICAL ACTIVITY IN A CELL, INCLUDING METHODS AND COMPOSITIONS USEFUL TO REGULATE GENE FUNCTION

摘要

A method for neutralizing an intracellular nucleic acid-binding protein's biological activity in a cell by exposing the protein to an intracellular concentration of a single stranded (ss)DNA or RNA, or a double stranded (ds)DNA or RNA possessing a recognition motif for the protein, sufficient to cause binding of the protein to the (ss)DNA, (ss)RNA, (ds)DNA or (ds)RNA and thereby block the intracellular protein's biological activity.