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Amides of eicosatetraynoic acid, their pharmaceutical and cosmetic use, their preparation and process for the preparation of eicosatetraynoic acid
Amides of eicosatetraynoic acid, their pharmaceutical and cosmetic use, their preparation and process for the preparation of eicosatetraynoic acid
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机译:二十碳四烯酸的酰胺,其药物和化妆品用途,其制备方法以及制备二十碳四烯酸的方法
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摘要
Compound characterised in that it corresponds to the formula:… C5H11(C IDENTICAL C-CH2)4-CH2CH2COR (I)… in which R is an amino group of structure …IMAGE… in which R1 and R2, which are identical or different, denote a hydrogen atom, a C1-C8 lower alkyl radical, linear or branched, substituted by at least one hydroxyl group, it being possible for this C1-C8 lower alkyl radical to be interrupted by one or more heteroatoms chosen from oxygen, nitrogen and sulphur, R1 and R2 not denoting simultaneously a hydrogen atom and it being possible for R1 and R2 to form with the nitrogen atom to which they are attached a heterocyclic ring comprising, as additional heteroatom, one or more nitrogen, oxygen or sulphur atoms, it being possible for this heterocyclic ring to be essentially substituted by an alkyl or a hydroxyalkyl, it being also possible for the amino group to originate from a sugar, and their salts with inorganic or organic acids. …??These compounds are employed especially in the treatment and the prophylaxis of allergic diseases and in the treatment of dermatitis and inflammatory diseases.
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