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ANTI-UROKINASE MONOCLONAL ANTIBODY BEARING MATRIX CAPABLE OF SEPARATING AND PURITYING WORKINASE FROM BIOLOGICAL SOURCES
ANTI-UROKINASE MONOCLONAL ANTIBODY BEARING MATRIX CAPABLE OF SEPARATING AND PURITYING WORKINASE FROM BIOLOGICAL SOURCES
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机译:可从生物来源分离和纯化尿激酶的抗尿激酶单抗抗体基质
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摘要
A class of new IgG1 monoclonal antibodies, directed to an epitope on human urokinase, which selectively bind to high molecualr weight urokinase (54,000), or a single-chain precursor thereof, without binding to low molecular weight urokinase (33,000) have an affinity constant for urokinase which is suitable for use in an immono-adsorption-based purification system and does not impair the enzymatic activity of urokinase. This antibody is also useful in immunoassays.
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