A process for preparing a polymeric anticancer agent comprising exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

摘要

The present invention relates to a synthetic method for developing an anticancer agent having excellent anticancer properties and low toxicity, and a test for the process and anticancer properties, and more specifically, exo-3, 6-epoxy-1,2,3,6-tetrahydrophthalic anhydride Poly (ETA)], a mixture of ETA and various vinyl monomers at a ratio of 10-80 mol%, was prepared by mixing poly (ethylene-(ETA-co-VP), which is a copolymer containing ETA and a polymer having a molecular weight of 3,000-90,000 by reacting with an initiator concentration of 0. 1-20% by weight at 40-60C for 4-72 hours, (ETA-co-AAc), Poly (ETA-co-AA), Poly (ETA-co-AA) The present invention relates to the preparation and the anticancer properties of the hydrolysates of cohesive enzymes ETACOH-1, ETACOH-2, ETACOH-3, ETACOH-4, ETACOH-5 and ETACOH-6.