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A method for the preparation of pharmaceutical hard capsules and apparatus for the production thereof.

机译:一种制备药物硬胶囊的方法及其生产装置。

摘要

The method of this invention for manufacturing capsules causes the solution of thermo-gelling material to gelatinize once, and then drys the gel. Therefore the process of manufacturing capsules is less affected by drying conditions, thus providing capsules of uniform wall thickness without wrinkle. In the apparatus of this invention, circulating capsule pins are dipped in the solution of thermo-gelling material, thus the solution adheres to the pins. And the pins are rotated upside down, thus thickness of the solution adhering to the pins becoming uniform. Then the pins are retained in the vessel maintained at a higher temperature than the gelling temperature of the solution, and the solution adhering to the pins is accelerated to gelatinize. Thus formed gel is dried through a drying device, and the dried gel, i.e. capsules, is removed from capsule pins.
机译:本发明的用于制造胶囊的方法使热胶凝材料的溶液一次凝胶化,然后干燥凝胶。因此,制造胶囊的过程受干燥条件的影响较小,因此提供了壁厚均匀且无皱纹的胶囊。在本发明的设备中,将循环的胶囊销钉浸入热胶材料的溶液中,因此溶液粘附到销钉上。并且销钉上下颠倒旋转,因此粘附到销钉上的溶液厚度变得均匀。然后,将销钉保持在保持在比溶液的胶凝温度更高的温度的容器中,并且加速粘附到销钉上的溶液的糊化。这样形成的凝胶通过干燥装置干燥,并且将干燥的凝胶即胶囊从胶囊销中取出。

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