New derivatives of dihydro - 2,3 arylacoylaminoalcoyl - 3 4h - 29 - 1,3 one is - 4, their preparation and their application as medicinal products that are useful in international application no.

摘要

The invention relates to the new 3-arylalkylaminoalkyl-4H-1,3-benzoxazin-4-one derivatives of general formula IMAGE I in which: R1, R2, R3 and R4, which may be identical or different, denote a hydrogen, a branched or unbranched lower alkyl group or an alkyloxy, halo, nitro, amino, acylamino or dialkylamino group, and R1 and R2 on one hand and R3, R4 on the other hand can fuse to give a divalent group and more especially -OCH2O-, -OCH2CH2O- and -CH=CH-CH=CH-; R5 and R6, which may be identical or different, denote a hydrogen, a saturated or unsaturated, branched or unbranched alkyl group containing from 1 to 15 carbon atoms or a cycloalkyl group, and R5 and R6 can fuse to give a -(CH2)p- group with p=2 to 7; R7 denotes a hydrogen, a saturated or unsaturated, branched or unbranched alkyl group containing from 1 to 15 carbon atoms, a cycloalkyl group, a substituted or unsubstituted aryl and a substituted or unsubstituted arylalkyl; the values of m and n, which may be identical or different, can vary from 1 to 4 inclusive; as well as the therapeutically acceptable organic or inorganic salts of I. The compounds are useful as medicinal products in the treatment of disorders of the cardiovascular system.