NEW CEPHALOSPORINS COMPRISING A 2-THIA CEPHEME CORE, PROCESS FOR THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, AND THE NEW INTERMEDIATES OBTAINED.

摘要

The subject of the invention is the products of general formula (I): BR/ (CF DRAINING IN BOPI) BR/ BR/ syn isomer, in R or S form or in a R mixture Wherein R1 represents either a heterocyclic radical or a radical -S-Het, BR/ (CF DRAWING IN BOPI) BR/ BR/ E or Z form, BR/ Rb and Rc represent a hydrogen atom or an acyl group, and A and A 'represent a hydrogen atom, a base equivalent, or the residue of an easily cleavable ester group or CO 2 A represents CO2 - as well as the salts of the products of formula (I) with the mineral or organic acids. BR/ These products have interesting properties that justify their use in antibiotic therapy. / P