首页> 外国专利> IMPROVER FOR AMINO ACID-BASED PERIPEHRAL NERVE DISORDER

IMPROVER FOR AMINO ACID-BASED PERIPEHRAL NERVE DISORDER

机译:基于氨基酸的周围神经疾病的研究

摘要

PURPOSE: To obtain the subject chemical useful for preventing, treating and improving peripheral nerve disorder, AIDS, ulcerative colitis, rheumatism, inflammation, etc., composition improving action on nerve transmission rate.scavenging action on radical, comprising a specific cysteine derivative. ;CONSTITUTION: A cysteine derivative of the formula (R1 is H or acetyl; R2 is H, lower alkyl; R3 is H or carboxymethyl) (e.g. N-acetylcysteine) or its pharmacologically permissible salt as an active ingredient is mixed with an excipient such as lactose, corn starch or crystalline cellulose, a binder such as polyvinyl alcohol, methyl cellulose or hydroxypropylmethyl cellulose, a disintegrator such as starch or carboxymethyl cellulose, a lubricant such as magnesium stearate or talc and a flavor such as cocoa powder or menthol and pharmaceutically manufactured to give the objective improver for amino acidbased peripheral nerve disorder having improving action on nerve transmission rate.scavenging action on radical.;COPYRIGHT: (C)1994,JPO
机译:用途:获得用于预防,治疗和改善周围神经疾病,艾滋病,溃疡性结肠炎,风湿病,炎症等的主题化学物质,该组合物改善对神经传递速率的作用。对自由基的清除作用,包括特定的半胱氨酸衍生物。 ;组成:式(R 1 为H或乙酰基; R 2 为H,低级烷基; R 3 为H的半胱氨酸衍生物或羧甲基)(例如N-乙酰半胱氨酸)或其药理学上允许的盐作为有效成分与赋形剂(如乳糖,玉米淀粉或结晶纤维素),粘合剂(如聚乙烯醇,甲基纤维素或羟丙基甲基纤维素)混合,崩解剂(如淀粉或羧甲基纤维素,润滑剂(例如硬脂酸镁或滑石粉)和调味剂(例如可可粉或薄荷醇),并经药物生产,可制成氨基酸类周围神经疾病的客观改善剂,对神经传递速率具有改善作用,对自由基具有清除作用;版权所有:(C)1994,日本特许厅

著录项

  • 公开/公告号JPH06279397A

    专利类型

  • 公开/公告日1994-10-04

    原文格式PDF

  • 申请/专利权人 EISAI CO LTD;

    申请/专利号JP19930095132

  • 发明设计人 TOYODA TAKANORI;SAGARA MIKIO;SATO YUZURU;

    申请日1993-03-31

  • 分类号C07C323/52;A61K31/195;

  • 国家 JP

  • 入库时间 2022-08-22 04:50:29

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