NOVEL IMIDAZOLE DERIVATIVES, PROCESS OF THEIR PREPARATION AND ANTIMYCOTIC PREPARATIONS IN WHICH SAID IMIDAZOLES ARE COMPRISED

摘要

Novel imidazole derivatives of the formula …IMAGE… in which Ar denotes phenyl which is optionally substituted by halogen, lower alkyl or lower alkoxy, biphenylyl, naphthyl or thienyl, R1 denotes hydrogen or lower alkyl, Alk denotes straight-chain or branched alkylene having 1 to 10 carbon atoms, Y denotes oxygen, sulphur, sulphinyl or sulphonyl, n denotes one of the numbers 0, 1 or 2, Z denotes sulphur or sulphinyl, m denotes the number 0 or 1, where, if Y denotes sulphur, sulphinyl or sulphonyl, m denotes the number 0 and if Y denotes oxygen, m is the number 1, R2 denotes cyclohexyl, phenyl which is optionally substituted by hydroxyl, halogen, trifluoromethyl, lower alkyl or lower alkoxy or naphthyl, biphenylyl or pyridyl. The imidazole derivatives have excellent antimycotic properties when used in human and veterinary medicine.