Carbostyril derivatives, process for their preparation and pharmaceutical composition containing such carbostyril derivative

摘要

A novel carbostyril derivative and salt thereof represented by the formula (1), CHEM (wherein R is a group of the formula CHEM ((wherein R1 is a C1-C3 alkoxy group)), a group of the formula CHEM ((wherein R2 and R3 are each, at the same time, a chlorine atom, a bromine atom; and R4 is a hydrogen atom or a chlorine atom)), 2-methyl-3-nitrophenyl group, 3,5-dichlorophenyl group, or a group of the formula CHEM ((wherein R5 is a chlorine atom or a bromine atom; and R6 is a methyl group)); the carbon-carbon bond between 3- and 4-position in the carbostyril skeleton is a single or double bond). The novel carbostyril derivative and salt thereof represented by the formula (1) is useful agent for treating schizophrenia.