Crystals of 7 beta -[(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetamido]-3-(1- imidazo[ 1,2-b]-pyridazinium)methyl-3-cephem-4-carboxylate hydrochloride or a solvate thereof, which are stable and improved in solubility in water, are usable for an excellent antibacterial agent.
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