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NEW BENZOCYCLOHEPTIENES, AND BENZOXEPINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PRODUCING THEM
NEW BENZOCYCLOHEPTIENES, AND BENZOXEPINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PRODUCING THEM
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机译:新的苯环庚类和苯佐西汀,包含它们的药物组合物及其制备方法
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PCT No. PCT/EP93/03445 Sec. 371 Date Aug. 5, 1994 Sec. 102(e) Date Aug. 5, 1994 PCT Filed Dec. 7, 1993 PCT Pub. No. WO94/13658 PCT Pub. Date Jun. 23, 1994The subject of the invention is compounds of general formula: IMAGE I in which: X represents O or CHR, R1, R2, R3 and R4, which are identical or different, represent a hydrogen atom or a C1-C7 alkyl group, it being possible for R1 to additionally form a bond with R; R5 represents a hydrogen atom, a hydroxyl group or R5, taken together with R7, forms a bond or a O; group; R6 represents a group of formula: IMAGE in which R10 and R11, taken together with the carbon atom to which they are attached, form a nitrogenous heterocyclic group, and their N-oxides and pharmaceutically acceptable salts. These compounds are powerful activators of potassium channels.
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