7-BETA-(Z)-2-(2-AMINO-4-THIASOLYL)-2-HYDROXYIMINOACETAMIDE-3-(1,2,3-TRIAZOL-4-YL)-THIOMETHYLOTHIO-3-CEPHEMO-4-CARBOXYLIC HYDROCHLORIDE, CRYSTALLINE HYDRATE OF 7-BETA-(Z)-2-(2-AMINO-4-THIASOLYL)-2-HYDROXYIMINOACETAMIDE-3-(1,2,3-TRIAZOL-4-YL)-THIOMETHYLOTHIO-3-CEPHEMO-4-CARBOXYLIC HYDROCHLORIDE, METHOD OF OBTAINING THESE COMPOUNDS, PHARMACEUTICAL PREPARATION AND METHOD OF FIGHTING AGAINST BACTERIAE

摘要

7 beta -[(Z)-2-(2-Amino 4 thiazolyl)-2-hydroxyiminoacetamido]-3-(1,2,3-triazol-4-yl)thiomethylth io-3-cephem-4-carboxylic acid hydrochloride and its crystalline hydrate, which have a potent antibiotic activity and are low toxic and pharmaceutically stable, thereby useful as an active ingredient of clinically useful antibiotic formulations, and the production thereof.