METHOD FOR PRODUCING CLAUSENAMIDE AND NEOCLAUSENAMIDE AND THEIR DERIVATIVES.

摘要

The invention relates to a process for the preparation of (+/-) 3(S*),4(R*),5(R*), 7(S*)-1-methyl-3-hydroxy-4-phenyl-5-( alpha -hydroxy-benzyl)pyrrolidin-2-one (clausenamide) and (+/-) 3(S*), 4(R*),5(S*), 7(R*)-1-methyl-3-hydroxy-4-phenyl-5-( alpha -hydroxybenzyl)pyrrolidin-2-one (neoclausenamide) of the general formula (I) …IMAGE… in which R1 has the meaning given in the description, and their derivatives.