STEROIDS USEFUL FOR PREPARING COMPOUNDS OF THE 20-KETOPREGNAN SERIES

摘要

specific disclosure.the invention relates to compounds of formula (iii):(iii)characterized in that hal is a halogen atom atwith the exception of the fluorine atom, and r is the.a hydrogen atom or a methyl radical, r2 represents amethyl or ethyl, the nodes a, b, c, d areone or more double bonds and are not replacedone or more functions or substituted by hydroxy oronly non protected or protected by one or morehalogen atoms, alkyl radicals or by one or morealkoxy containing 1 to 4 carbon atoms or aseveral alku00e9nyle or alkynyle radical containing from 2 to 4carbon atoms, r is a halogen atom.hydroxyl radical, an alkoxy radical having 1 to 6 carbon atomsaralkoxy radical having carbon atoms of from 7 to 15.a carbon radical.), in which r3 and r4 are identical or different.represents a hydrogen atom, an alkyl radical havingfrom 1 to 6 carbon atoms, a radical aralkyle with 7to 15 carbon atoms, and r3 and r4 form together withthe nitrogen atom to which they are linked to a heterocyclic ringwith or without a heteroatom selected from the othernitrogen and oxygen atoms, and r represents a radicalin having 1 to 6 carbon atoms, a radicalaralkylthio arylthio or having up to 15 carbon atoms.with the exception of products 23, 23 - dichloro -, ethylcholanamide and 3 - acetoxy - 23,23 - dichloro - n - ethyl - cholanamide.the compounds of formula (iii) are useful for thepreparation of products for the series 20 keto pregnane.