BENZOYL PEROXIDE AND QUATERNARY AMMONIUM LIPOPHILIC SALICYLATE-BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES, PARTICULARLY IN THE TREATMENT OF ACNE

摘要

SHORT DESCRIPTION The invention relates to a topical composition, pharmaceutical or cosmetic containing, in combination in a physiologically acceptable medium, benzoyl peroxide and at least one lipophilic quaternary ammonium salicylate corresponding to the general formula (I): (I) wherein R1, R2, R3 and R4, identical or different, denote an alkyl or alkylecycloalkyle, optionally substituted or interrupted; or R3 and / or R4 is (are) a group: wherein 0? not ? 4 and p denote 0 or 1, R 8 denotes a hydrogen atom or an alkyl, alkenyl, alkylcycloalkyl or alkylaryl; or R4 is a radical alkylènephényl; or R1 and R2 form an aromatic or non-aromatic heterocyclic ring, saturated or unsaturated; or R1, R2 and R3 form with the nitrogen atoms of the polycyclic derivatives; and R5 denotes a group of formula Wherein n is an integer ranging from 0 to 16. The compositions according to the invention are useful in the treatment of skin disorders and dermatoses, such as in particular acne, skin ulcer, warts and dyskératinisa- tions of the skin.