cs31a protein capsule subunit modified by at least one heterologous peptide, cs31a protein capsule comprising said subunit, micro-organisms having such subunits on their outer membrane, and methods for preparing and using same

摘要

PCT No. PCT/FR93/01281 Sec. 371 Date Feb. 16, 1996 Sec. 102(e) Date Feb. 16, 1996 PCT Filed Dec. 21, 1993 PCT Pub. No. WO94/14967 PCT Pub. Date Jul. 7, 1994A CS31A protein capsule subunit having an aminoacid sequence modified by at least one heterologous peptide, the CS31A protein capsule comprising said subunit, and micro-organisms having the CS31A protein capsule with its subunit aminoacid sequence modified by at least one heterologous peptide, are disclosed. Methods for preparing said subunits, CS31A protein capsules comprising same, and micro-organisms having CS31A protein capsules, as well as the use thereof for preparing vaccines, producing peptides and preparing immunoassays, are also disclosed.