ION CHROMATOGRAPHIC SEPARATIONS USING STEP AND LINEAR VOLTAGE WAVEFORMS AT A CHARGE-CONTROLLABLE POLYMERIC STATIONARY PHASE

摘要

A method and apparatus for chromatographic separations comprising a conductive-polymer stationary phase for controlled interaction with ionic species. The conductive polymer stationary phase is held at an initial voltage while analyte containing ionic species is added. The ionic species interact with and are held by the stationary phase. Voltage across the stationary phase is varied by linear or step waveforms which alters the stationary phase charge characteristics. Ionic species are selectively released from the stationary phase as its charge characteristics change due to the individual charges of each ionic species. Ionic species released from the stationary phase are flushed from the column by an ionic mobile phase.