Process for the extraction of factor VIII-von willebrand factor (FVIII:C-FVW) complex from total human plasma

摘要

A process for the extraction of Factor VIII - von Willebrand Factor (FVIII:C - FvW) complex from total human plasma is described, comprising unfreezing the plasma at room temperature after stabilization, selective absorption on anionic exchanger of factors constituting the protrombinic complex, extraction, on anionic exchanger as well, of Factor VIII - von Willebrand Factor (FVIII:C - FvW) complex and a further purification by means of a cationic exchanger of FVIII:C - FvW suitably stabilized and inactivated.