NOVEL 19-NOR STEROIDS HAVING A THIOCARBON-CONTAINING CHAIN IN THE 11BETA POSITION, A METHOD FOR PREPARING SAME AND INTERMEDIATES THEREFOR, MEDICINAL USES THEREOF AND COMPOSITIONS CONTAINING SAID STEROIDS

摘要

The invention relates to compounds of formula (I) wherein R 17 and R '17 are such that: either R 17 and R' 17 together form a ketone, hydrazono, oxime, methylene; or R17 is hydroxyl, hydroxymethyl, acyloxy and R '17 represents a hydrogen, an alkyl, alkenyl or alkynyl optionally substituted; R3 is hydrogen, alkyl; R16 is hydrogen, halogen, alkyl; m is 0, 1 or 2; X, Y and Z are such that: X represents a methylene, arylene or arylenoxy linked to the steroid by a carbon atom; Y represents a linear or branched chain aliphatic saturated or unsaturated, optionally interrupted by oxygen, Z represents a linear or branched alkyl, or an aryl or arylalkyl, and the addition salts thereof, their preparation, their use as medicaments, compositions containing them and new intermediates obtained.