Use of panthenol, pantetheine or pantothenate, capable of stimulating endogeneous cortico-steroid biosynthesis - in compsn. for treating e.g. bronchial asthma, rheumatism, hay fever or osteoarthritis

摘要

The use of panthenol (I), pantetheine (II) or pantothenic acid salts (III) is claimed for prepn. of a compsn. for treatment of diseases, esp. neurodermatitis, bronchial asthma, rheumatic diseases, hay-fever or sinusitis maxillaris. Also claimed is a compsn., for treating diseases (esp. as above) contg. a unit dose of 500mg of calcium pantothenate (IIIa), specifically for oral or parenteral admin. USE/ADVANTAGE - (I)-(III) stimulate endogenous corticosteroid biosynthesis, and increase blood levels of adrenocorticotropic hormone (ACTH) and cortisol in humans and animals. They are thus useful for therapy of disorders treatable with corticosteroids, e.g. neurodermatitis, bronchial asthma, chronic polyarthritis, osteoarthritis, sporting injuries, hay fever and chronic recurrent sinusitis maxillaris.