Dihydropyridine - connection to the improvement of the cores of the expansion and the inhibition of the cardiac hypertrophy.

摘要

A venous extensibility improving or cardiac hypertrophy suppressant agent characterized by containing a dihydropyridine compound of the general formula: CHEM wherein R1 is a nitrophenyl group and R2, R3 and R4 are each same or different lower alkyl group or a pharmaceutically acceptable salt thereof, and a process for using such compound or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for improving venous extensibility and suppressing cardiac hypertrophy in mammal including human being.