A method for the preparation of polyglycerol fatty acid ester mixtures and the use in cosmetic, pharmaceutical and chemically - technical preparations

摘要

Prodn. of polyglycerol fatty acid ester mixts. is effected by reacting a polyglycerol component (I) with a fatty acid component (II) in the presence of a catalyst using a (I):(II) molar ratio of 0.3:1.5 to 1.5:0.5. The reaction is effected by heating at 140 deg.C, pref. 145 deg.C (sic); reducing the pressure to 600 mbar, pref. 500 mbar (sic); heating to 140-220 (pref. 145-190) deg.C using a stepwise or continuous heating programme; and reducing the pressure to 10-600 (pref. 20-500) mbar using a stepwise or continuous evacuation programme. Water is distd. off continuously. When the acid no. falls below 3, the prod. is cooled and opt. worked up and/or purified. (I) comprises (by wt.): 0.1-20% glycerol (G1), 20-35% diglycerol (G2), 30-40% triglycerol and 5-49.9% tetra- and higher polyglycerols (G4+). (II) comprises one or more satd. 8-18C fatty acids and has an unsatd. fatty acid content of 0-15 wt.%. Also claimed is a polyglycerol fatty acid ester mixt. comprising (by wt.): 0.1-20% G1 esters, 20-35% G2 esters, 30-40% G3 esters and 5-49.9% C4+ esters, where the fatty acid component is as above and the mixt. comprises 20-80% monoesters, 20-80% diesters, 0-15% tri- and higher esters and less than 5% free polyglycerol. Also claimed is a liq. thickener with skin-care properties, and an o/w emulsifier with skin-care properties for use in creams or ointments, both comprising an ester mixt. as defined above and produced by the above process.