Intrinsic - factor - - horseradish peroxidase - conjugates and a method for increasing the stability of the same

摘要

the present invention presents a non isotopie competitive assay for vitamin b12 (b12), using the horseradish peroxidase (hrp) - marked intrinsic factors (if) by coupling on heterobifunktionelle vernetzungsmittel. in addition, a method for stabilization of the resulting conjugates by pretreatment with n - ethylmaleinimid revealed.