首页> 外国专利> 1 beta, 7.8 trihydroxyvitamin d 2, 1 beta, 7.8 trihydroxyvitamin d 3 and its derivatives and methods for their manufacture.

1 beta, 7.8 trihydroxyvitamin d 2, 1 beta, 7.8 trihydroxyvitamin d 3 and its derivatives and methods for their manufacture.

机译:1β,7.8三羟基维生素d 2、1β,7.8三羟基维生素d 3及其衍生物和制造方法。

摘要

Novel compounds represented by formula (II) are disclosed. They can be easily converted into a fragment corresponding to ring A to be used in a process for binding a fragment corresponding to ring A to fragments corresponding to rings C and D by the oxidative cleavage of the C7-C8 bond according to a known method. The novel compounds of formula (II) can be obtained by allylic oxidation of the compound of formula (I) to directly introduce one oxygen-functional group into C1-position.
机译:公开了由式(II)表示的新型化合物。它们可以容易地转化成对应于环A的片段,用于根据已知方法通过C 7 -C 8键的氧化裂解将对应于环A的片段结合至对应于环C和D的片段的方法中。可以通过将式(I)化合物进行烯丙基氧化而直接将一个氧官能团引入C 1位置来获得式(II)的新型化合物。

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