Compounds having a vasodilatory effect and an inhibitory platelet aggregation effect and containing pharmaceutical preparations.

摘要

Novel compounds represented by the formula: CHEM wherein R1 represents an alkyl group having 1 to 3 carbon atoms, R2 represents an amino group or a group of formula CHEM in which R4 represents an alkyl group having 1 to 3 carbon atoms, R5 represents an alkyl group having 1 to 3 carbon atoms or may combine with R6 to form a five or six membered ring containing 4 to 5 carbon atoms, R6 represents a hydrogen atom or may combine with R5 to form a five or six membered ring containing 4 to 5 carbon atoms, R3 represents a hydrogen atom, an alkyl group having 1 to 3 carbon atoms or a halogen atom, X represents a carbonyl group or a methylene group, Y represents a sulfur atom or a vinylene group and pharmaceutically acceptable salts thereof which exhibit a vasodilating activity and inhibitory activity for platelet aggregation. Thus, they are useful as therapeutic agents for treatment of angina pectoris, hypertension, thrombosis and the like.