Use of trifluoromethylphenyltetrahydropyridines for the preparation of medicaments intended to combat disorders of intestinal motor skills

摘要

The invention relates to the use of trifluoromethyl- phenyltetrahydropyridines of formula : …IMAGE… in which Alk represents a straight- or branched-chain alkylene group having from 1 to 4 carbon atoms and R represents a cyano group, an acetyl group, a cycloalkyl group having 3 to 7 carbon atoms, a phenyl group, a p-tolyl group, a pyridyl group, a pyridyl 1-oxide group or a naphthyl group, and their pharmaceutically acceptable salts, for the manufacture of medicaments for the treatment of disorders of intestinal motor function, and especially the treatment of constipation. …??It also relates to 1-[2-(4-tolyl)ethyl]-4-(3-trifluoromethyl- phenyl)-1,2,3,6-tetrahydropyridine, its pharmaceutically acceptable salts and pharmaceutical compositions containing them.