首页>
外国专利>
Exopeptidase catalyzed site-specific bonding of supports, labels and bioactive agents to proteins
Exopeptidase catalyzed site-specific bonding of supports, labels and bioactive agents to proteins
展开▼
机译:外肽酶催化支持物,标记物和生物活性剂与蛋白质的位点特异性结合
展开▼
页面导航
摘要
著录项
相似文献
摘要
The invention provides a means for attaching a label, support or bioactive agent to a protein with an exopeptidase at a site that is remote from the active site of the protein. More specifically the invention is directed to a method for the attachment of an amino acid, amine and alcohol nucleophile to the carboxyl terminus of a protein. In one embodiment, a labeled nucleophile is attached to a protein such as an antibody. In other embodiments, the invention is directed to a method for the attachment of a protein to an immobilization support and to a method for the attachment of a bioactive agent to a protein.
展开▼