首页>
外国专利>
Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
展开▼
机译:固相载体上苯二氮卓类化合物的固相和组合合成
展开▼
页面导航
摘要
著录项
相似文献
摘要
Methods, compositions, and devices for synthesis of therapeutically useful compounds. The invention provides a rapid approach for combinatorial synthesis and screening of libraries of derivatives of therapeutically important classes of compounds such as benzodiazepines, prostaglandins and &bgr;-turn mimetics. In order to expediently synthesize a combinatorial library of derivatives based upon these core structures, general methodology for the solid phase synthesis of these derivatives is also provided. This disclosure thus also describes an important extension of solid phase synthesis methods to nonpolymeric organic compounds.
展开▼