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A composition and a method of using veratridine and epinephrine as a local anesthetic
A composition and a method of using veratridine and epinephrine as a local anesthetic
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机译:使用维甲酸和肾上腺素作为局部麻醉剂的组合物和方法
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摘要
A method of using veratridine to inhibit nerve impulses, and a composition of matter including veratridine and epinephrine, is provided. Application of veratridine proximal to a nerve causes depolarization of the nerve membrane, thereby blocking transmission of nerve impules. C- fiber selectivity is demonstrated in vitro in rabbit vagus nerves. Veratridine displays extended anesthetic activity over long periods of time when compared to similar local anesthetics, with no local toxicity. Systemic toxicity is reduced by co-injection with epinephrine.
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