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Production host and production manner null of rearrangement product of high
Production host and production manner null of rearrangement product of high
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机译:高重排产品的生产主机和生产方式无效
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摘要
This invention relates to improved host organisms and methods for producing recombinant products in high yields. More particularly, the present invention relates to cell strains carrying specific mutations within their DNA sequences which cause the organism to exhibit a reduced capacity for degrading foreign products and the use of these strains to produce increased yields of genetically engineered foreign proteins, polypeptides and other products. The methods disclosed in this invention advantageously permit the production, in high yields, of foreign recombinant proteins, polypeptides or other products in hosts which do not usually produce such products.
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