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Azulene derivatives, process for their synthesis and anti-ulcerative and anti-inflammatory agents comprising these derivatives
Azulene derivatives, process for their synthesis and anti-ulcerative and anti-inflammatory agents comprising these derivatives
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机译:Azulene衍生物,其合成方法以及包含这些衍生物的抗溃疡和抗炎剂
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摘要
New azulene derivatives of the general formula …CHEM… where: R1 is a lower alkyl group, a group of the general formula …CHEM… or a benzyl group, R5, R6 and R7 each representing H or a lower alkyl group and n being 1 or 2;… R2 and R3 each represents H or a lower alkyl group;… R4 is H or an alkoxy group;… and X is Na or Al(OH)2 are stable to light and heat and are useful as anti-ulcerative and anti-inflammatory agents. …??The azulene derivatives may be prepared by reacting a compound of the formula …CHEM… wherein R1, R2, R3 and R4 are as defined above with a sulfonating agent and converting the resulting sulfonic acid to its sodium or aluminium salt.
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