Method for producing an antigenic peptide or antigenic protein derived from the melanoma-associated antigen p97 and useful recombinant viruses, recombinant vectors and host cells.

摘要

Peptides or proteins which belong to a melanoma-associated antigen are described. These are prepared in large amounts using recombinant DNA techniques and/or chemical synthetic methods. The peptides or proteins can be used as immunogens in vaccine formulations which elicit an immune response able selectively to destroy melanoma cells in a vaccinated individual. When the peptides or proteins are expressed by a recombinant virus, it is possible to prepare vaccine formulations based on inactivated viruses or based on live viruses.