首页>
外国专利>
8-(3-substituted-1-piperazinyl)-7-fluoro-4-oxo-1,4-dihydrobenzo(b)(1,8)naphthyridine-3-carboxylic acids, their preparation and compositions containing them
8-(3-substituted-1-piperazinyl)-7-fluoro-4-oxo-1,4-dihydrobenzo(b)(1,8)naphthyridine-3-carboxylic acids, their preparation and compositions containing them
New benzo[b][1,8]naphthyridine derivatives of general formula (I), in which R1 is a hydrogen atom or a hydroxyl or alkyl radical, R2 is a hydrogen atom or an alkyl, fluoroalkyl, cycloalkyl (3 to 6 C), alkyloxy or alkylamino radical, R3 is a phenyl or phenylalkyl radical substituted with one or more halogen atoms or alkyl, cycloalkyl (3 to 6 C), alkyloxy, cyano, amino, alkylamino, dialkylamino, alkyloxyalkyl, hydroxyalkyl, hydroxyalkyloxy, methylenedioxy, aminoalkyl, alkylaminoalkyl or dialkylaminoalkyl radicals, or R3 is a heterocyclic radical, and R4 is a hydrogen atom or a fluorine atom, the alkyl radicals (1 to 4 C) being linear or branched, their salts, their preparation and compositions containing them. These new products are useful as antimicrobials, or in the treatment of AIDS. IMAGE (I)
展开▼
机译:通式(I)的新的苯并[b] [1,8]萘啶衍生物,其中R1为氢原子或羟基或烷基,R2为氢原子或烷基,氟代烷基,环烷基(3至6 C ),烷氧基或烷基氨基基团,R3是被一个或多个卤素原子或烷基,环烷基(3-6C),烷氧基,氰基,氨基,烷基氨基,二烷基氨基,烷氧基烷基,羟烷基,羟烷基氧基,亚甲基二氧基,氨基烷基,烷基氨基烷基或二烷基氨基烷基基团,或R 3为杂环基,且R 4为氢原子或氟原子,所述烷基(1至4 C)为直链或支链的,其盐,其制备物和包含它们的组合物。这些新产品可用作抗菌剂或治疗艾滋病。 <图像>(I)
展开▼