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SECONDARY METABOLISM ACTIVATION (SAF) FACTOR POLYPEPTIDE, GENE,PROMOTER AND USE FOR EXPRESSION IN STREPTOMYCES
SECONDARY METABOLISM ACTIVATION (SAF) FACTOR POLYPEPTIDE, GENE,PROMOTER AND USE FOR EXPRESSION IN STREPTOMYCES
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机译:二级代谢激活因子多肽,基因,启动子及其在链霉菌中的表达
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摘要
The cloning and characterization of a newly isolated gene, referred to as saf (secondary metabolism activation factor) is disclosed. This gene encodes a new amino acid polypeptide, referred to as the SAF polypeptide, which directly or indirectly modulates the expression of extracellular enzymes in Steptomyces. DNA units or fragments which encode the SAF polypeptide are also disclosed, as are vectors containing said DNA, host organisms transformed with such vectors, and processes for preparing extracellular enzymes or heterologous polypeptides by culturing such host organisms.
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