Materiale med acyl-CoA-kolesterol-acyltransferase-inhiberende aktivitet, samt fremstilling derav

摘要

FO-1289 substance comprising FO-1289A substance, FO-1289B substance, FO-1289C substance and FO-1289D substance, which has inhibitory activity for acylcoenzyme A cholesterol acyltransferase is produced by culturing Aspergillus Sp. FO-1289. The substance is useful for treatment and prevention of a disease attributed by accumulation of cholesterol.