首页>
外国专利>
METHOD FOR PREPARING NEW INTERMEDIATE COMPOUNDS FOR PEPTIDE SYNTHESIS AND PROCESS FOR SYNTHESIS OF PEPTIDE-AMIDES BY THE SOLID PHASE METHOD USING THE REFERRED COMPOUNDS
METHOD FOR PREPARING NEW INTERMEDIATE COMPOUNDS FOR PEPTIDE SYNTHESIS AND PROCESS FOR SYNTHESIS OF PEPTIDE-AMIDES BY THE SOLID PHASE METHOD USING THE REFERRED COMPOUNDS
展开▼
机译:固体相法制备用于肽合成的新型中间化合物的方法及使用该化合物的固相合成方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The invention relates to new compounds of the formula IMAGE (I) in which R1 denotes (C1-C8)-alkyl, R2 denotes an amino acid residue which is protected with a urethane protective group which can be eliminated with weak acid or base, or denotes an amino protective group which can be eliminated with weak acid or base, R3 denotes hydrogen or (C1-C4)-alkyl, and Y1-Y9 denote identical or different radicals hydrogen, (C1-C4)-alkyl, (C1-C4)-alkoxy or -O-(CH2)n-COOH (with n=1 to 6), with one of these radicals being -O-(CH2)n-COOH, or Y1, Y2 and Y5-Y9 denote identical or different radicals hydrogen, (C1-C4)-alkyl or (C1-C4)-alkoxy, Y3 denotes hydrogen or (C1-C8)-alkoxy and Y4 denotes -(CH2)n-COOH or -NH-CO-(CH2)n-COOH (with n=1 to 6). Processes for the preparation thereof and the synthesis of peptide amides by a solid-phase method using these new compounds (spacers) are described.
展开▼