derivatives of (hetero) tioeteri ethers and aromatic containing antiiperlipidemica activity, process for their preparation and pharmaceutical compositions containing them.

摘要

the new derivatives of aromatic ethers and tioeteri (straight) represented by the following general formula 1: (het) ar - x - y - ch2 ch2 - or - r (i), where: (het), ar represents a core arilico or eteroarilico mono -,bi - and tricyclic possibly substituted, x represents - o - or - s -, y represents - co -, a linear alkyl or ramified with from 0 to 8 carbon atoms, chor1.in which r1 s hydrogen or a group derived from a carboxylic acid acilico alifatico, aromatic or declination, with the proviso that r1.is hydrogen when (het) ar is a group guaninico, adeninico or adenosinico, - c = n - r2, in which r2 s hydrogen or an alkyl having linear or ramified 1a 10 carbon atoms, ch,a alcossile having 1 to 10 carbon atoms, a arilossile, a arilalcossile, nh2, nhconh2.- nhcsnh; and r represents a phenyl ester substituted in position 2 with a carboxylic group or (c1 - c20) alcossicarbonilico.in the group alcossilico may be linear or ramified have assets _ antiiperlipidemica.we also describe the process for their preparation and the pharmaceutical compositions which contain them.