antagonists of human interluchina - 6 totally incapable of forming a bond with gp 130, and their use for the preparation of pharmaceutical compositions.

摘要

PCT No. PCT/IT96/00084 Sec. 371 Date Oct. 28, 1997 Sec. 102(e) Date Oct. 28, 1997 PCT Filed Apr. 26, 1996 PCT Pub. No. WO96/34104 PCT Pub. Date Oct. 31, 1996The present invention relates to human interleukin-6 receptor antagonists which are incapable of binding to the receptor chain responsible for transduction of the signal associated with interleukin-6, namely, gp130. The present invention also relates to DNA encoding human interleukin-6 receptor antagonists.