Esters of etretinic or related macrolide and lincosamidicos of type antibiotics, process for their preparation and pharmaceutical compositions containing them and cosmetic.

摘要

ESTERS OR TYPE ETETRINICO CO`N related macrolides and LINCOSAMIDOS corresponding to the formula wherein R is a radical derived from a macrolide or UNCOSAMIDA A, R is a methyl radical, R2 is H, or R1 and R2 together form A RADICAL vinylene (- CH = CH -), R3 is HO an alkyl radical of 1 to 4 CYZ is a divalent radical of the formula: R4 is a hydrogen atom HO an alkyl radical with 1 to 4 CO FORMULA: ITS iSOMERS , mixtures and salts of such esters. Use in the treatment of various dermatoses PARTICULARLY THE TREATMENT OF ACNE.