MONOCLONAL ANTIBODIES AGAINST LENS EPITHELIAL CELLS AND METHODS FOR PREVENTING PROLIFERATION OF REMNANT LENS EPITHELIAL CELLS AFTER EXTRACAPSULAR EXTRACTION

摘要

Cytotoxic compositions and methods for theiruse are provided for preventing proliferation ofremnant lens epithelial cells following extracapsularextraction. The cytotoxic compositions comprisemonoclonal antibodies specific for lens epithelialcells which are introduced into the anterior chamber ofthe eye where they bind specifically to any lensepithelial cells. The method may be used at the timeof extracapsular cataract extraction or may be usedsubsequently to remove a second cataract resulting fromproliferation of remnant lens epithelial cells.