Ungulate preblastocyst derived embryonic stem cells and use thereof to produce cloned transgenic and chimeric ungulates

摘要

Totipotent ungulate embryonic stem cell lines, e.g., of bovine origin, derived from preblastocyst precursor cells are taught. These cell lines are used for cloning of ungulates, for the production of transgenic cell lines, and for the production of transgenic and chimeric ungulates.