Compositions containing green porphyrins to destroy malignant cells in mononuclear cell populations

摘要

A method to prepare bone marrow or other hemopoietic cells free of malignant cells for autologous transplants is described. The mononuclear cells from the marrow are treated with a green porphyrin (Gp) to effect the uptake of said Gp by malignant cells selectively, and then irradiated with a wavelength of light absorbed by said Gp to effect the destruction of the malignant cells. The purged marrow cells can then be used for autologous transplantation.