ANTI-VIRAL SULFUR-ANALOGUES OF 1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL (DEOXYNOJIRIMYCIN)

摘要

Novel derivatives of 1-deoxynojirimycin are disclosed which have thio or sulfinyl substituents at C-2 or C-3. These compounds are useful inhibitors of lentiviruses such as visna virus and human immunodeficiency virus. Methods of chemical synthesis of these derivatives and intermediates therefor are also disclosed.