首页> 外国专利> Method of using alpha, omega-dicarboxylic acid as fibrinogen reducing agent (USE OF α, ω-DICARBOXYLIC ACIDS AS FIBRINOGEN REDUCERS)

Method of using alpha, omega-dicarboxylic acid as fibrinogen reducing agent (USE OF α, ω-DICARBOXYLIC ACIDS AS FIBRINOGEN REDUCERS)

机译:使用α,ω-二羧酸作为纤维蛋白原还原剂的方法(使用α,ω-二羧酸作为纤维蛋白原还原剂)

摘要

The present invention is to prepare a drug having a fibrinogen-lowering effect on the? Ω-dicarboxylic acid of the following formula (I) or a carboxyl derivative which can be hydrolyzed in the body of the? Ω-dicarboxylic acid It is about how to use it.;Wherein X and Y may be the same as or different from each other, hydrogen, halogen, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, hydroxyl, cyano, carboxyl, C 1 -C 6 -Alkoxy-carbonyl or carbamoyl; R 1 and R 2 may be the same or different and are hydrogen or C 1 -C 6 -alkyl; Q is a linear saturated or unsaturated alkylene chain of 2-14 carbon atoms, in which one or more C-atoms can be replaced with a cycloalkyl ring, petyl or hetero ring.
机译:本发明是要制备一种对纤维蛋白原具有降低作用的药物。下式(I)的Ω-二羧酸或可在β-己内酰胺体中水解的羧基衍生物。 Ω-二羧酸有关如何使用它;其中X和Y可以彼此相同或不同,氢,卤素,C 1 -C 6 -烷基,C 1 -C 6 -烷氧基,羟基,氰基,羧基,C 1 -C 6 1 和R 2 可以相同或不同,并且可以是氢或C 1 -C 6 -烷基; Q是2-14个碳原子的线性饱和或不饱和亚烷基链,其中一个或多个C原子可被环烷基环,戊基或杂环取代。

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