2-Substituted adenosines with A-2 receptor affinity with A-2 receptor affinity RTI ID = 0.0

摘要

The present invention relates to adenosine analogs that selectively act on adenosine receptors and generally function as adenosine agonists. From in vitro studies, it is known that specific physiological effects are characterized as a result of this selectivity, and that in vitro adenosine receptor activity correlates with in vivo adenosine receptor activity. The pharmaceutical preparations of the compounds of the present invention can be prepared on the basis of the selective binding activity of the compounds described herein and can be used to minimize problems such as lowering the blood pressure without lowering the heart rate,