METHOD OF PREPARING OF HIGH-POROUS POLYURETHANE FOAM COMPOSITION WITH IMMOBILIZED TRYPSIN

摘要

FIELD: medicine. SUBSTANCE: trypsin is bound preliminary with prepolymer containing toluylenediisocyanate 80/20 and polyisocyanate at ratio (1.8-2.2):(1.3-1.0) following by elongation of polymer chain using component containing activating agent triethylenediamine. EFFECT: preparing of biocompatible, biodegradable, high-porous enzyme-containing polymer, increased enzyme stability, time action and availability for substrates.