METHOD OF SYNTHESIS OF 5-METHYL,6-6³H-2,4-(1H,3H)-PYRIMIDINEDIONE

摘要

FIELD: organic chemistry. SUBSTANCE: product: 5-[methyl,6-6³H]-2,4-(1H, 3H)-pyrimidinedione. Thymine or 5-hydroxymethyluracil applied on the palladium catalyst (5% Pd per BaSO₄) is treated with gaseous tritium at 145-200 C for 40 min. Synthesized compound is used in biochemistry. EFFECT: improved method of synthesis. 2 cl, 2 tbl